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Mood and Terpenes: What Published Research Has Examined
Searches about mood deserve a careful page. No hemp product is approved to address any condition, including depression, and nothing here is medical advice — if you’re struggling, a licensed professional is the right resource. Below is what the research literature actually contains about terpenes and mood-related measures.

What researchers have examined
The most-cited human study is from 1995: a small trial in which citrus fragrance (rich in limonene) was examined in hospitalized patients with depressive states. Rodent studies have examined limonene and linalool using behavioral models that researchers use as rough proxies for mood. A widely cited 2011 pharmacology review cataloged these terpene findings and called for controlled human research, most of which has still not been done.
What the research can’t tell you
One small 1990s study and a set of rodent models cannot support any conclusion about hemp products and human mood. No such conclusion is drawn or implied anywhere on this site.
Sources
- Komori T, et al. (1995). Effects of citrus fragrance on immune function and depressive states. Neuroimmunomodulation, 2(3):174–180. [doi]
- Russo EB. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7):1344–1364. [doi]
More in the library: all research summaries · the terpene guide